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Go to Editorial ManagerThe toxicity of permanent implants is the main concern. The release of ions from the substrate leads to toxicity. Because of how the human body works biologically, the toxicity of corrosion compounds is a byproduct of wear and fretting debris. aimed to improve the corrosion resistance of a 316L stainless steel substrate. Bio ceramic Nano-hydroxyapatite (HA) was coated using the Electrophoretic Deposition (EPD) technique. Stainless steel has good mechanical properties and high compatibility, but it suffers from body fluid attack due to its chloride content, which can penetrate the passivation layer, resulting in the release of chromium and nickel ions. Tissues and organs are damaged by the ions and debris that are released. To address this problem, it was coated with bioceramic using the EPD method. Suspensions of various powders—hydroxyapatite, magnesium oxide, zinc oxide, and the composite—were prepared and coated by electrophoretic deposition. The coated samples were dried at room temperature to ensure a homogeneous coating structure. The zeta potential test for magnesium oxide and hydroxyapatite suspensions was positive, while zinc oxide and complex suspensions were negative. One of the important parameters for achieving electrolyte and implant balance is the open circuit potential (OCP). A substantial change towards a more noble direction (less negative) was seen in the OCP-coated (316 L) alloy, suggesting excellent thermodynamic stability. Tafel extrapolation analysis was used to obtain the corrosion potential (Ecorr) and corrosion current density (Icorr) values of composite-coated stainless steel 316L, which are generally derived from the polarization curve. The findings that are in line with the MgO, HA, and ZnO coatings show a significant decrease in corrosion current (Icorr), an increase in corrosion potential (Ecorr), and a decrease in corrosion rate from (4.386 × 10-¹ mm/y) Stainless Steel 316 L to (1.417 × 10-² mm/y) MgO Coated and (1.222 × 10-³ mm/y) (65%MgO+25%ZnO+10%HA coated).
The aim of this work is to use Fiber Bragg Grating (FBG) to detect the breast cancer at its earliest stages based on the Photoacoustic (PA) hybrid technique. The fiber Bragg gratings sensitivity to acoustic wave, effect of grating length, effect of grating refractive index modification, and ultrasonic frequency on the wavelength sensitivity and intensity sensitivity of the ultrasonic sensor (FBG) for ultrasonic waves were investigated using a simulation programs. A wavelength for the photoacoustic (PA) excitation laser was chosen with respect to a high absorption by the tumor and with low absorption to the surrounding tissue (normal tissue); for higher contrast absorption between them. Fiber Bragg can be used as a sensor to detect the acoustic wave emitted from the tumor (depending on the photoacoustic principle). In this study, k-wave a MATLAB toolbox was used to simulate photoacoustic wave which is detected with fiber Bragg grating simulation, using Optisystem program. The acoustic wave was transferred to FBG by using Optisystem-MTLAB communication programs to detect tumors.
Hydrogels are among the most versatile material classes used in biomedical applications. The material is of considerable interest in various fields of medicine due to its excellent features, such as high-water content, biocompatibility, and adjustable mechanical properties. The highlighted study thoroughly reviews Schiff-base thiadiazole-modified hydrogels as a novel functional material class, emphasizing their applicability in medical science. The addition of the Schiff-base and free thiazole groups to the hydrogel matrix introduces new antimicrobial activity, drug delivery, and bioadhesive attributes. An elaborate description of the methods employed to copolymerize thermoresponsive hydrogels with carbazole of thiadiazole as a binding group through free radical polymerization and visible light initiation is given under the first step of this general approach. The section on these hydrogels' physical and chemical properties was then added with a bias on morphological characterization, water uptake studies, and mechanical properties of the materials. After that, the discussion on more applications commenced, and among these, the following sections study them in the field of life-saving biomedical devices such as wound healing, tissue engineering, delivery of drugs, and biosensing prepared biosensing. A key emphasis is given to those interaction modes between Schiff-base thiadiazole groups and the biological systems that fulfil the hydrogels' healing mechanisms. These interaction modes, which include [specific modes], play a crucial role in the hydrogels' healing mechanism. The mentioned scholarship, in addition, dwells on the issues and barriers of such materials and gives thorough and valid judgements about the present and future of the matter. This review and the hard evaluation provide a thorough insight into Schiff-base thiadiazole-modified hydrogels' transformative impacts across the entire biomedicine area. A new approach is achieved by this review, in which the audience is made conscious and fully informed by presenting the most recent discoveries concerning the potential of Schiff-base thiadiazole-modified hydrogels to bring about innovative biomedical applications.
Functionally graded material is one of the promising sectors of the material since because of the great ability to control with required product properties could be strongly used in biomedical applications exclusively in the implants sector, this review paper demonstrates briefly about the most prominent known manufacturing methods and focusing on the implants coated by FGM layer manufactured by using EPD method because the EPD has significant properties it could produce FGM layer in the Room temperature without depending on chemical reactions or heat adding, Biomedical application need highly accuracy when we deal with material that directly contact with human tissue because the heat effect could be change the biocompatibility properties and also the chemical reactions could make toxic effect on the produced implants, All these reasons make the EPD one of the favorable method for the FGM coated Implants. this paper will summarise and give the Gide line for the researcher about the most important substrate and suspension materials used in the EPD method and its application.