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Go to Editorial ManagerThe current study presents the plasma cutting process of 2 mm thickness of AISI 1020 carbon steel. The experiment conducted by taking into the account the effect of two process parameters, including cutting current of 15 and 20 A with cutting speed in range of 500 - 4000 mm/min, on the kerf formation, microstructure and microhardness.The results showed that at low cutting current of 15 A the melting occurred at the workpiece surface without cutting action. Increase the current to 20 A led to full penetration of the workpiece material at low and high cutting speed, with kerf width between 1.26 mm and 1.1 mm for cutting speed of 500 mm/ min and 4000 mm/ min, respectively. The plasma arc cutting speed has a high impact on the heat-affected zone HAZ and microstructure development with coarse grains at the HAZ at low cutting speed of 500 mm/min and constant current of 20A, increase the plasma cutting speed led to decreasing the grain size. The microstructure of the HAZ exhibited a presence of perlite and ferrite with some martensite structure. The highest microhardness of the HAZ of 220.8 HV was found in the sample processed at 20 A current and high cutting speed of 4000 mm/ min. However, the minimum microhardness of the HAZ of 156.7 HV was found in the sample processed at 20 A current and low cutting speed of 500 mm/ min.
Enhanced signal emission from nano (ESEN) coated titanium target over than that from normal untreated one was investigated. Four samples of Ti alloy were adjusted, the first sample was left untreated, the second and third samples were coated with plasma sputter at thicknesses of 35nm and 70nm, and the last sample was treated with a drop of colloidal Au nanoparticle solution prepared by laser ablation. The (ESEN) was monitored with Ti at 413.7 and 393.3 nm. It was obtained that the spectral emission from the nano-laser ablation had a greater improvement than that from the plasma sputter coating or bulk target. Enhancement factors were found up to ten folds, and show the spectroscopic line induced patterns by laser energies (100,150, and 200mJ) from the alloy with and without gold.
This study has been performed to compare the compartmental modeling of two types of extravascular routes, sustained-release (SR) oral dosage forms and intramuscular (IM) injection. Twenty healthy volunteers received a single dose of 100 mg Diclofenac Sodium (DS) sustained-release tablet, then 75 mg DS Intramuscular injection after two weeks washout period. The concentrations of DS in plasma were measured using reverse-phase high-performance liquid chromatography (HPLC). The data analyzed using compartmental modeling, with single time-variant input and output. Primary kinetic parameters for both formulations, ( , , ) and other kinetic parameters were evaluated. The result shows that the IM injection needs a shorter time to reach the maximum concentration with convergent bioavailability to SR oral dosage forms, in another hand the data of IM injection fitted to single-compartment model with a correlation coefficient of 0.93 and the data of SR tablet fitted to two-compartment models with a correlation coefficient of 0.97.